A oftalmopatia tireoidea é uma doença autoimune da órbita intimamente associada com o hipertireoidismo (doença de Graves), embora ambas as condições. Do ponto de vista clínico, a doença de Graves caracteriza-se por aumento difuso e hiperatividade da glândula tireóide, associada ou não a oftalmopatia. Oftalmopatia tireoidea revisitada*. Thyroid A oftalmopatia tireoidea é doença orbitária autoimune intimamente com o hipertireoidismo (doença de Graves).

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Janowitz P, Ackmann S. The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted Country, Minnesota. Clin Endocrinol Oxf45pp.

Radioactive iodine therapy in Graves’ hyperthyroidism

Eur J Endocrinol ; Antithyroid drugs and Graves’ disease: Natural history of thyroid associated ophthalmopathy. Clinical features and outcome of subacute thyroiditis in an incidence cohort: J Paediatr Child Health.

Effect of methimazole pretreatment on serum thyroid hormone levels after radioactive treatment in Graves’ hyperthyroidism. Adjunctive cholestyramine therapy for thyrotoxicosis.

Valoración y tratamiento de la oftalmopatía de Graves | Endocrinología y Nutrición

Radioiodine treatment for pediatric Graves’ disease. Rectal administration of propylthiouracil in the treatment of Graves’ disease.

Treatment of hyperthyroidism in infancy and adolescence. Is routine supplementation therapy calcium and vitamin D useful after total thyroidectomy? Metastatic thyroid cancer presenting as thyrotoxicosis: J Med Assoc Thai.

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Prediction of cure and risk of hypothyroidism in patients receiving I for hyperthyroidism. The use of antithyroid drugs in pregnancy and lactation. Percutaneous ethanol injection of hyperfunctioning thyroid nodules: Smith J, Brown RS.

Abnormal liver function test in Graves’ disease: The importance of surgeon experience for clinical and economic outcomes from thyroidectomy. Graves’ disease is the most frequent cause of hyperthyroidism.

Acute changes in thyroid function in patients treated with radioactive iodine.

Surgery for Graves’ disease: O hipertireoidismo deve ser tratado com DAT D. An optimal treatment for pediatric Graves’ disease is radioiodine. High prevalence of antineutrophil cytoplasmic antibody positivity in childhood onset Graves’ disease treated with propylthiouracil.

Graves’ disease with moderate-severe endocrine ophthalmopathy-long term results of a prospective, randomized study of total or subtotal thyroid resection.

Effect of long-term continuous methimazole treatment of hyperthyroidism: Thyroid dysfunction from antineoplastic agents. Thyrotoxicosis in prepubertal children compared with pubertal and postpubertal patients.

Prospective multicentre study on the prediction of relapse after antithyroid drug treatment in patients with Graves’ disease.

Thyroidectomy is optimal treatment for Graves’ disease. Radioiodine treatment of hyperthyroidism – prognostic factors for outcome. Outcome of thyroid function in Graves’ patients treated with radioiodine: Prognosis of small thyroid cancer in patients with Graves’ disease.

Cardioselective beta-blockers in patients with reactive airway disease: Radioiodoterapia e Oftalmopatia de Graves. Could improved ultrasound and power Doppler replace oftalmopahia radioiodine uptake to assess thyroid disease?


Graves’ ophthalmopathy is considered to be an autoimmune disorder and a component of Graves’ disease, and represents a process confined to the orbit where the connective tissues become inflamed and accumulate glycosaminoglycans. The cumulative doses recommended vary but 20 Gy delivered over two weeks is usually used. Radioactive iodine is increasingly being used as definitive therapy, because it long has proven to be a safe, nonexpensive and effective treatment.

How to cite this article. To summarize the information on the effects of treatment of hyperthyroidism, restoration of euthyroidism by thionamides is associated with an amelioration of eye disease. Clinical features of patients with Graves’ disease undergoing remission after antithyroid drug treatment. A new MRI method for the quantitative evaluation of extraocular muscle size in thyroid ophthalmopathy.

Lower dose prednisone prevents radioiodine-associated exacerbation of initially mild or absent graves’ orbitopathy: Progression of Graves’ ophthalmopathy has been observed after radioiodine treatment, and thyroidectomy per se seems to carry a very low risk, if any, of causing Graves’ ophthalmopathy progression.